[3] It is a highly potent butyrophenone derivative and is the most potent neuroleptic in the European market, with chlorpromazine equivalency as high as 75 to 100 (about 150 to 200% the potency per dose of haloperidol).

[4] It is sometimes prescribed to sex offenders as a condition of their parole, as an alternative to anti-androgen drugs such as cyproterone acetate.

[5] Benperidol was discovered by Janssen Pharmaceutica in 1961 and has been marketed since 1966.

It is mainly used in Germany, but it is also available in Belgium, Greece, the Netherlands, and the United Kingdom.

[8] Benperidol is absorbed well and undergoes extensive first pass metabolism.