The most important proposal in the memorandum was to provide a legal basis for a regulation that gives doctors the right to reserve themselves against referral and treatment in the event of serious conflicts of conscience related to life and death, in practice especially abortion.

[3] The proposal, which was called prehistoric by top politicians in its own ranks,[4] was poorly received, which among other things led to a record turnout during the International Women's Day parade on 8 March 2014.

[6][7] In March 2016, Høie was appointed by United Nations Secretary-General Ban Ki-moon to the High-Level Commission on Health Employment and Economic Growth, which was co-chaired by presidents François Hollande of France and Jacob Zuma of South Africa.

[9] In October 2019, Høie criticized skier Andreas Håtveit, who caused controversy when he expressed concern about the level of where the standard was put for leaders in KRIK.

[10] During the COVID-19 pandemic in Norway, Høie was a leading figure representing the government, routinely appearing at press conferences alongside prime minister Erna Solberg and health officials announcing new rules, restrictions and regulations.

[12] After the government announced that politicians would be getting vaccines in late May, Høie was one of the ministers who turned down the offer, alongside members of the Storting, both opposition and coalition partners.

[16][17] Early into his tenure, Høie met with delegations from Sandnes and Strand to discuss the ongoing uncertainty of readjusting Forsand's border.

[19] In June, the ministry rejected the proposal for Forsand to join Strand, and that it should stay a part of Sandnes, which caused a stir among pro-Strand champions.