[5] Portions of St. Louis Lambert International Airport are within the city limits.

[8] According to the United States Census Bureau, the city has a total area of 4.97 square miles (12.87 km2), all land.

[9] The 2020 United States census[14] counted 8,228 people, 3,435 households, and 2,243 families in Berkeley.

The racial makeup of the city was 81.8% African American, 14.3% White, 3.5% Hispanic or Latino, 0.4% Asian, 0.2% Native American, 0.1% Pacific Islander, 1.6% from other races, and 1.7% from two or more races made up its population.

24.9% of all households were made up of individuals, and 8.3% had someone living alone who was 65 years of age or older.

The racial makeup of the city was 76.69% African American, 20.64% White, and 1.60% from two or more races.

And 0.37% Asian, 0.26% Native American, 0.02% Pacific Islander, and 0.43% from other races made the city's population.

23.9% of all households were made up of individuals, and 7.8% had someone living alone who was 65 years of age or older.

Prior to its merger with Boeing, McDonnell Douglas was headquartered in the same complex in Berkeley.

[21][22] Elementary schools outside of Berkeley serving sections of the city include Johnson-Wabash in Ferguson and Walnut Grove in Calverton Park.

[27][29] The Berkeley School District opened in 1937 after a dispute over where a school for black people should be located, with the black residents of southern Kinloch and the white residents of northern Kinloch opposing each other.

The high school, located in what is now Berkeley, was exclusively for white students.

In December 2003 the former Berkeley High School closed due to expansion of Lambert-St. Louis Airport.