Don Bernardino Fernández de Velasco, 1st Duke of Frías, Grandee of Spain (c. 1450 – 9 February 1512) was a Spanish nobleman and prominent military figure of the last stages of the Reconquista.
He participated in the conquest of Granada, where his father died, and became one of its firsts Viceroys.
On 20 March 1492 he was granted the title of Duke of Frías by the Catholic Monarchs.
After becoming a widow, he married secondly Doña Juana de Aragón, Lady of Castilnovo, an illegitimate daughter of King Ferdinand II of Aragon, with whom he had another daughter, Doña Juliana de Velasco y Aragón, 1st Countess of Castilnovo, and future consort Duchess of Frías by her marriage to her cousin.
He had no legitimate male issue, so his titles passed on to his younger brother Don Íñigo Fernández de Velasco, 2nd Duke of Frías.