Bernardo de Sandoval y Rojas (20 April 1546 – 7 December 1618) was a Spanish bishop and cardinal who was Grand Inquisitor of Spain from 1608 to 1618.

His uncle, Cristóbal de Rojas y Sandoval, Bishop of Oviedo granted him the tonsure on 13 November 1555.

He attended the University of Alcalá, where he studied under Ambrosio Morales and received his bachillerato on 18 June 1566; his licentiate on 25 October 1567 and a doctorate in arts on 3 November 1567.

He was consecrated by Cardinal Rodrigo de Castro Osorio, Archbishop of Seville, on 20 April 1586.

He received his galero on 26 February 1601, at which time he was granted the titular church of Santa Anastasia.