Berwickshire, Roxburgh and Selkirk is a constituency of the British House of Commons, located in the south of Scotland within the Scottish Borders council area.

A mostly rural constituency, it includes the towns of Coldstream, Duns, Eyemouth, Galashiels, Hawick, Jedburgh, Kelso, Melrose and Selkirk.

Under the 2023 review of Westminster constituencies which came into effect for the 2024 general election, the boundaries are unchanged and are defined as comprising the following wards of the Scottish Border Council: Michael Moore held the seat from its creation in 2005, and was MP for the predecessor seat of Tweeddale, Ettrick & Lauderdale from 1997 to 2005.

At the 2015 general election, Moore and the Liberal Democrats were pushed into third place in the constituency, and the seat was narrowly won by Calum Kerr of the Scottish National Party over the Conservative candidate, John Lamont, by 328 votes.

He held the seat with a reduced majority of 5,148 votes, due to a swing towards the SNP and Liberal Democrats.