Best Friends Animal Society, (BFAS) is an American nonprofit 501(c)(3) animal welfare organization based in Kanab, Utah with satellite offices in Atlanta, Georgia, Bentonville, Arkansas, Houston, Texas, Los Angeles, California, New York City, and Salt Lake City, Utah.

Ally Financial and Bowman pledged to make a total of $30,000 in donations to Best Friend affiliated shelters in race host cities during the 2021 season.

After the Foundation church moved to its current grounds in 1984, the founders eventually informally called it "Best Friends" until 1991 when it began formally operating as Best Friends Animal Sanctuary, a no-kill shelter[16] located in Southwestern Utah in Angel Canyon (formerly Kanab Canyon) near Kanab.

[18] Every kind of animal has its own area, considered neighborhoods, which includes Bunny House, Dogtown and Cat World among others.

[21] Best Friends was the only bidder for the contract to run the shelter that had cost the taxpayers $19 million to build just three years prior.

[25] Best Friends teams entered the Hurricane Katrina disaster area on September 2, 2005, and stayed eight months in and around New Orleans.

[29] Also after Katrina, Best Friends helped Pets Alive, an animal shelter in New York state, and rescued around 800 cats from an institutional hoarding situation in Nevada.

[36] Released in October 2015, The Champions is a documentary that covers the stories of five dogs and their impact they had had on their adopters and how society looks at pit bulls rescued from fighting cases.

[41] In August 2008, Best Friends and PetSmart Charities funded a program called "Feral Freedom" for free-roaming community cats in Jacksonville, Florida.