Men's 12.5 km biathlon events at the 2006 Winter Paralympics were contested at Pragelato on 11 March.

There were three events, and standings were determined by applying a disability factor to the actual times achieved.

Additionally, for each missed shot, a penalty of one minute was added to the calculated time.

The visually impaired event was won by Vitaliy Lukyanenko, representing  Ukraine.

[1] The sitting event was won by Vladimir Kiselev, representing  Russia.