This series was the first civilian edition to launch under the new three-year contract that was announced in March 2015 which guaranteed the show remained on Channel 5 until 2018.

[5] It was the shortest-running series of the British Big Brother at that point, until the 2023 ITV revival surpassed it with a length of only 42 days.

On 9 March 2016, it was announced that Big Brother showrunner and Initial managing director Nick Samwell-Smith was to depart from the company in May.

[11] On 20 May 2016, it was announced that Shannon Delwiche, an executive producer, was to depart and be replaced by Rebecca Kenney-Smith, having previously been Big Brother's series editor in 2015.

[12] On 20 May 2016, a 20-second teaser aired on Channel 5 featuring both Emma Willis and Rylan Clark-Neal, also teasing that "The game is changing".

The teaser featured Emma Willis and Rylan Clark-Neal, teasing "The game is changing", "Nothing is as it seems" and "Get ready for an unseen force".

After returning to her home country, housemate and fifth place finalist Evelyn Ellis appeared on Married at First Sight Australia.

A typical week begins with nominations, followed by the shopping task, and then the eviction of a Housemate during the live Friday episode.