Big Business is a 1988 American comedy film starring Bette Midler and Lily Tomlin, each playing two roles, as sets of identical twins mismatched at birth.

The nature versus nurture farce adapts The Comedy of Errors, but with female siblings in contemporary society: one of each twin being reared in a wealthy urban setting, while the others grew up in a poor rural environment.

Forty years later, the Shelton sisters are now co-chairwomen of Moramax in New York City, a conglomerate that is the successor to their father's business interests.

The Sheltons eventually arrive at the hotel and take the suite next door, leading to a series of near-misses between the four sisters.

As the day unfolds, Sadie Shelton meets Alberici and becomes enamored with him as they flirtatiously discuss the upcoming sale.

Worried that he will disrupt the sale, the two men attempt to keep Roone distracted while enlisting the help of Rose Shelton.

Jim Abrahams said he staged one of the boardroom scenes based on an experience he had when a large agency used many employees to get him to sign with them.

Rotten Tomatoes reports that 52% of critics gave the film a positive rating, based on 23 reviews, with an average score of 5/10.

[4] Sheila Benson from the Los Angeles Times called Big Business a "bright whirligig of a movie" and added: "As you watch its buoyant hilarity, the intricacies flow smoothly as honey off a spoon [...] Like a sensational party the night before, Big Business may not bear the closest scrutiny in the cold light of day, but it gives an irresistible glow at the time.

[6] In his review for The New York Times, Vincent Canby remarked that Big Business, "though it never quite delivers the boffo payoff, is a most cheerful, very breezy summer farce, played to the hilt by two splendidly comic performers...Sometimes [the film's writers] do have trouble in characterizing the two sets of twins, allowing them to blend in such a way that the comic edge finally becomes blurred.

[10] In the United States, Big Business debuted within the top three on the box-office chart and became a modest success, eventually grossing $40.2 million during its domestic run.

In 2011, Big Business was among a selection of titles from Touchstone and Hollywood Pictures to be licensed to Mill Creek Entertainment on behalf of Disney, and a DVD and Blu-ray disc were released of the film.

In December 2017, Big Business and Scenes from a Mall were re-released on DVD and Blu-ray by Kino Lorber under license from Walt Disney Studios Home Entertainment.