Premiering on August 31, 2019, it serves as the pre-game show for Fox College Football, and in particular, Big Noon Saturday—the network's weekly 12:00 p.m ET/9:00 a.m PT kickoff window.

It is hosted by Rob Stone, and features former national champion and 2004 Heisman Trophy winning USC Trojans quarterback Matt Leinart, former national champion and 2009 Heisman Trophy winning Alabama running back Mark Ingram II, former Notre Dame Fighting Irish quarterback Brady Quinn, and former Bowling Green, Utah, Florida, and Ohio State coach Urban Meyer as panelists, with Bruce Feldman acting as Fox's CFB insider, as well as Tom Verducci, who usually does baseball for Fox, and Tom Rinaldi, both working on feature reports.

The program was unable to compete with ESPN's popular and established College GameDay, with Fox only being able to sustain an average viewership of 70,000.

[8][6] Sports Illustrated described the show as being "built around" Urban Meyer (who retired as head coach of the Ohio State Buckeyes at the end of the 2018 season, and had previously been an ESPN analyst).

Fox executive producer Brad Zager explained that his presence was meant to help provide "intelligent dialogue" to the show.

[10] On November 4, 2020, for undisclosed reasons citing Centers for Disease Control and Prevention and Los Angeles County Department of Health Services guidance, Fox announced that the November 7, 2020 edition of Big Noon Kickoff would not feature the program's usual panel, and that the program would be shortened to one hour.

This criticism has particularly come from Penn State fans, as they argue that Big Noon Kickoff diminishes the quality of the school's traditional White Out game.

Penn State typically aims to schedule their White Out tradition for a night game, but Penn State's marquee Big Ten matchups are usually featured on Big Noon Kickoff, requiring the school to schedule their White Out game for what fans consider to be lesser-quality opponents.

[26] In the 2021 season, Big Noon Saturday overtook the SEC on CBS as having the highest average viewership for College Football telecasts.