Big Pine (formerly Bigpine)[3] is a census-designated place (CDP) in Inyo County, California, United States.

It lies on U.S. Route 395, the main north–south artery through the Owens Valley, connecting the Inland Empire to Reno, Nevada.

The plaque beneath the young giant sequoia (pictured), referred to as the Roosevelt Pine, at the road junction says it was planted in 1913 to commemorate the opening of Westgaard Pass to auto traffic.

The landmark giant sequoia was felled on September 28, 2020, after most of its foliage had died following its sole water source drying up in the 2017-18 drought.

[4] North from Westgaard Pass lies the Ancient Bristlecone Pine Forest, home to the oldest trees in the world.

To the West, Glacier Lodge Road leads high up Big Pine Creek into the Sierra, to lakes, hiking trails, fishing, and rock climbing underneath the Palisades Range and the Palisade Glacier.

According to the United States Census Bureau, the CDP has a total area of 3.0 square miles (7.8 km2), over 99% of its land.

Matt Williams, a professional baseball player and manager, lived there for part of his life.

Hollywood character actor Elisha Cook, Jr., known for such classic films as The Maltese Falcon and Shane, had a home in Big Pine and died here in 1995.

[10] Federally, Big Pine is in California's 8th congressional district, represented by Democrat John Garamendi.

Piper, the daughter of Pike and Annie Piper, sued the school district, claiming the state law establishing separate schools for “Indian children” and other children of Asian parentage was unconstitutional.

Nonetheless, Alice Piper was invited as a pupil and her victory along with the passage the Indian Citizenship Act, on the same day opened the door for her and other Native American children to attend public schools in the state of California.