An invitation extended to the University of Chicago, one of the founding members of the Big Ten who withdrew from the conference in 1946, was accepted.

[9] Following its admittance to the Big Ten in 1990, the CIC invited Pennsylvania State University to join the consortium.

[13] On June 29, 2016, the name of the consortium was changed from "Committee on Institutional Cooperation" to "Big Ten Academic Alliance".

[14] BTAA universities award 29% of all agriculture Ph.D.s, 18% of engineering Ph.D.s, and 18% of humanities Ph.D.s in the United States annually.

[14] The BTAA's collaborative efforts span the academic enterprise of its members, including: A related institution to the BTAA, the Big Ten Cancer Research Consortium (BTCRC) unites the cancer research centers of Big Ten universities through collaborative oncology trials.