Biggsville is a village in Henderson County, Illinois, United States.

Illinois Route 94 passes through the center of the village, leading north 29 miles (47 km) to Aledo and south 25 miles (40 km) to La Harpe.

According to the 2021 census gazetteer files, Biggsville has a total area of 0.34 square miles (0.88 km2), all land.

There were 147 housing units at an average density of 436.20 per square mile (168.42/km2).

27.50% of all households were made up of individuals, and 8.50% had someone living alone who was 65 years of age or older.