While most older vampires have good memories, Bill has an exceptional ability to recall precise details, faces, and conversations.

In Dead Until Dark, Sookie saves Bill from being "drained" by a husband and wife seeking to sell his blood for profit.

(Vampire blood, colloquially known as "V" in the series, is a highly addictive performance enhancing drug, aphrodisiac, and hallucinogen for humans.)

In Club Dead, the relationship decisively ends when Eric discovers and informs Sookie about Bill's mission to investigate her for the Vampire Queen of Louisiana.

Bill first appeared in the “Bon Temps vampire speaks" video posted on BloodCopy.com, one of seventeen official companion websites created to complement the HBO original series True Blood.

[3] Bill is one of only four characters to appear in every episode, the other three being protagonist Sookie Stackhouse, her brother Jason, and Merlotte's Bar and Grill short order cook, Lafayette Reynolds.

After he is kicked out into the sunlight, Bill learns that faerie blood makes vampires temporarily immune to the sun.

In the fourth season, Bill becomes the Vampire King of Louisiana after staging a coup d'état against Queen Sophie Anne with the help of the Authority.

After consuming her blood, Bill is destroyed and resurrected as a more powerful vampire who is: impervious to staking; no longer needs an invitation to enter a human home; and involuntarily experiences visions of the future.

In the final season, Bill becomes infected with "Hepatitus-V": a fatal virus genetically engineered by the human government to exterminate vampires.