List of General Hospital characters introduced in the 1990s

After a successful surgery, she regained her sight, and Serena was ecstatic when her parents, Scott and Lucy, eventually got married and adopted a baby girl they named Christina Baldwin.

Later that year on Christmas Eve, Lucy married Kevin Collins and Serena was happy to gain an older sister named Olivia Locke.

Barrett, Leopold Taub, Faison, and Lord Ashton later form a cartel corner the market on international trade with the use of a dangerous carcinogen, carbon disulfide.

Stefan is the second son of villain Mikkos Cassadine, who once attempted to freeze the world with a weather machine in the famous 1980s Luke and Laura storyline, and his equally evil wife Helena.

During the grand Bacchanalia on Spoon Island, a ball celebrating her engagement to Stefan, Katherine fell off a parapet at the mansion, the victim of a failed attempt to murder Helena by Luke and Alexis.

Stefan attempted to kill Nikolas's real love, Emily Quartermaine, but pushed Lucky's girlfriend Summer (a Laura look-alike), off the cliff by mistake.

At this time as well, Luke Spencer kidnapped and put Stefan on "trial" in front of the entire Port Charles television audience, taped by Dillon Quartermaine.

John assumed the edgier name of Jagger, and fell in with a rough crowd, but his heart was still good—all it took to bring that out of him was some tender, loving care from young Karen Wexler.

Karen returned to Port Charles in 1997 as a young doctor in General Hospital's intern program, where she discovered she was going to be working closely with Dr. Joe Scanlon.

After getting a call, he and a few FBI agents shut down a sting operation ran by Anna Devane (Finola Hughes) and Jordan Ashford (Tanisha Harper).

[26] In 2023, Soaps.com contributor Charlie Mason placed Lois at number thirty-one on his ranked list of General Hospital's 40+ Greatest Characters of All Time, with his reasons being "The Brooklyn accent.

Kevin helped Mac and Felicia track his psychotic twin down at a fun-house and rescue Georgie, though the killer let himself die in the building's violent explosion rather than be locked away in the hospital again.

Unfortunately, on New Years Eve 2022, his daughter Esme set fire to the storage room using a match in order to escape Nikolas, then she intentionally falls off the parapet into the ocean.

While on the island, he holds both Ava and Felicia captive, and the whole situation ends with Mac shooting and killing Ryan, while his daughter gives birth to his grandson, Ace.

"[31] In 2023, Charlie Mason from Soaps She Knows placed Ryan and Kevin as a shared entry (at #33 and #32) on his ranked list of General Hospital's 40+ Greatest Characters of All Time, commenting "Arguably the ultimate good-and-evil-twin pairing, these siblings have been making the residents of Port Charles say, "Oh, brother!"

In January 2015, Kevin (temporarily portrayed by Anthony Starke) attempts to help Jason Morgan, believing his name to be Jake Doe, remember his true identity.

In 2023, Charlie Mason from Soaps She Knows placed Ryan and Kevin as a shared entry (at #33 and #32) on his ranked list of General Hospital's 40+ Greatest Characters of All Time, commenting "Arguably the ultimate good-and-evil-twin pairing, these siblings have been making the residents of Port Charles say, "Oh, brother!"

Lily overhears a conversation between Lois Cerullo, Ned Ashton, and Mac Scorpio, who have convinced Brenda to wear a wire to get information on Sonny's mob dealings.

Bill is the cousin of the Spencer family who had just come to town with his young son, Sly Eckert, and recently divorced form his mother, Nancy.

Harlan Barrett, Leopold Taub, Cesar Faison, and Larry Ashton formed a cartel to control global business via the use of a toxic substance, carbon disulfide, manufactured at a cannery they purchased as a clever ruse for their operations and a place to brew the drug with which they intended to rule the world.

Also during this time, Faison often makes illicit deals with WSB head, Sean Donely, including one to destroy Anna's marriage to Robert Scorpio.

Faison, with assistance from henchmen Desiree and Jacquess, leads Frisco and Sean on a wild goose chase through his Parisian winery before allowing them to rescue Felicia.

Meanwhile, back in Port Charles, Robin Scorpio finds part of a crystal that Faison had been searching for, prompting him to trick Scott Baldwin into selling him Wyndemere Manor.

[52] Barrett later forms a cartel with Leopold Taub, Cesar Faison (Anders Hove) and Larry Ashton (Hugo Napier) to control global business.

[63] On February 9, 1994, the wedding of Mac Scorpio (John J. York) and Felicia Jones (Kristina Wagner) is interrupted by Ryan Chamberlain (Jon Lindstrom), Paul and Jenny marry instead.

It is later revealed he has really returned to try and take down Sonny Corinthos (Maurice Benard) while keeping Robin Scorpio-Drake (Kimberly McCullough) away from her family and friends under Jerry Jacks (Sebastian Roché)'s orders as his new accomplice.

In October 2016, he was arrested by Anna Devane (Finola Hughes) and Jordan Ashford (Vinessa Antoine) and sentenced to 30 years in prison for his role in the murders including that of Sabrina Santiago’s (Teresa Castillo).

They, along with Alexis, and Jax, attempt to elope in Las Vegas, only to have that plan foiled, when Gertrude shows up, and informs them that without a formal wedding, witnessed in front of their family and friends, her inheritance will not be honored.

Karen Wexler MD was a fictional character from the ABC daytime soap opera General Hospital, and spin-off series Port Charles.

When Karen and Frank learn of vampires plaguing Port Charles, they join in the efforts to destroy Caleb Morley (Michael Easton), nearly dying when a room they were all in caught fire.