William Charles Stafford (August 13, 1938 – September 19, 2001) was a professional baseball player who pitched in the Major Leagues from 1960 to 1967.

Stafford was a successful pitcher for the New York Yankees from 1961 to 1962, winning a combined 28 games in two seasons.

He appeared in the World Series 3 times for the Yankees from 1960 to 1962, and was the winning pitcher in Game 3 of the 1962 World Series versus the San Francisco Giants.

In September 2001, Stafford died in his home at the age of 63 of a heart attack.

This biographical article relating to an American baseball pitcher born in the 1930s is a stub.