William George Werle (December 21, 1920 – November 27, 2010) was an American left-handed Major League Baseball pitcher from Oakland, California.

[5] In a benefit game for Hammond General Hospital in Modesto, California, Werle was one of three San Francisco Seals pitchers to face Sergeant Joe DiMaggio.

Stationed at the Santa Ana, California, Army Air Base, Dimaggio did not reach safely in four at bats.

The tie was not broken because of a league rule prohibiting an inning from beginning after 11:50 p.m.[9] He won 17 and lost seven with the Seals who were managed by Lefty O'Doul.

[14] The Pittsburgh Pirates released catcher LeRoy Jarvis to the Seals as partial payment for the rights to Werle in January 1949.

[15] As a National League rookie Werle survived a ninth inning rally at Ebbets Field in May 1949 to beat the Dodgers, 5–3.

Only a single run scored when Red Schoendienst hit a sacrifice fly which plated Solly Hemus.

It was mentioned that he arrived at his hotel with roommate, George Metkovich, after seven innings of a night game in Beaumont, Texas.

[24] In a game against the New York Giants on June 16 he relieved Eddie Yuhas in the ninth inning with two men on base.

Schmidt gave up a grand slam to Bobby Thomson, who hit his first pitch over the left field roof just inside the foul line at the Polo Grounds, to win the game for the Giants.

[26] Werle gave an up a long homer to Dave Philley in a relief outing against the Cleveland Indians in April 1954.

[27] Gus Zernial tagged Werle for a home run in the ninth inning of a game with the Philadelphia Athletics in June.

[31] Werle was named interim manager of the Hawaii Islanders of the Pacific Coast League in August 1961.

He managed Phoenix that season and was just 19 days short of becoming eligible for the major league pension plan, so the Giants put him on the active list as an extra coach.