He co-starred in the 2017 film The Sense of an Ending (as the younger version of Jim Broadbent's lead character) and the miniseries The Witness for the Prosecution in the pivotal role of the defendant in a murder case, Leonard Vole.

[6] In 2019, Howle starred alongside Richard Gere and Helen McCrory in the BBC drama series MotherFatherSon, which was written by Tom Rob Smith and he and Jodie Comer made cameo appearances in Star Wars: The Rise of Skywalker as Rey's parents Dathan and Miramir.

In 2021, he starred in the BBC series The Serpent[7] as Herman Knippenberg, and on BritBox's The Beast Must Die as Nigel.

[8] He also appeared in Under the Banner of Heaven as Allen Lafferty who struggled his faith after his wife Brenda's (Daisy Edger-Jones) murder.

[10][11] In 2024, Howle portrayed a 1970s boxer in Kid Snow,[12][2] and starred in the Netflix limited series The Perfect Couple as Benji Winbury, the son of the rich family.