[5] Bio Farma's history began during the Dutch East Indies period, when the colonial government founded Parc-vaccinogène (State Vaccine Development Agency) on 6 August 1890.

Since its inception, Parc-vaccinogène focused on eliminating infectious diseases, which leads to its cooperation with Pasteur Institute.

[3] During the administration of J.P. van Limburg Stirum, Hendrik Tillema recommended to move the capital of Dutch East Indies to Bandung due to its natural conditions and hilly terrain, making it easier to defend.

The idea was gradually accepted and began to be implemented by the Dutch colonial government in early 1920s after it was supported by Prof. J. Klopper, Rector of Technische Hogeschool te Bandoeng at the time.

Government and private offices along with other agencies began moving to Bandung, including the foreign trade office, salvation army, government bodies and 's Lands Koepok Inrichting en het Instituut Pasteur, which stayed in Bandung until the present day.