They were never affiliated with FIFA or UEFA, because Biscay is represented internationally by the Spain national football team.

In the first half of the 20th century, the provincial federation selected a representative team for friendly matches, and also took part in two editions of the inter-regional Prince of Asturias Cup, the first of which in 1922-23 ending in a quarter-final exit at the hands of Asturias after a dramatic 4–3 loss in the replay (the original game ended 1-1), but they managed to exact revenge in the following tournament when they faced Asturias in the quarter-finals again, this time winning 4–2 with goals from Carmelo, Laca and Travieso, but in the semi-finals, they were knocked-out by eventual champions Catalonia 0–1.

[1] Prior to the split between Gipuzkoa and Biscay, their players also formed a combined 'North' team (nominally including Cantabria, but dominated by Basque players) which evolved into the Basque Country team.

[4][5] The Biscay professional selection had reformed for the Castilian Federation's 'golden jubilee' in 1963, playing Andalusia,[6] and in June 2013 they did so again to face Athletic Bilbao, celebrating the 100th anniversary of both the federation's foundation and the opening of San Mamés stadium, as well as being its last match before demolition.

Despite being unable to include the opposition's employees in their squad, Biscay won the fixture 1–0 (Athletic introduced several retired players for cameo appearances in the later stages).