Bishop Byrne High School was a Catholic high school in Port Arthur, Texas.

In 1983 all of the teachers were lay teachers except for a single nun; the school administration believed having more clergy on staff would show a stronger religious image and encourage more people to enroll.

The owners sold the building, and Christus Southeast Texas established outpatient operations in it.

[1] The Bishop Byrne Alumni Association is in operation.

This article about a high school in Texas is a stub.