Felicianus, the patron saint of the city, though certainly not the first bishop, was consecrated by Pope Victor I and martyred under Decius (24 January); the exact dates of his history are uncertain.

On 10 March 1146, Cardinal Giulio Romano of S. Marcello, Legate of Eugenius III convoked a council in Foligno.

The council was attended by the bishops of Narni, Amelia, Spoleto, Todi, Assisi, Perugia, Cagli, Gubbio, Urbino, Montefeltro, Rimini, Pesaro, Fossombrone, Senigallia, Ancona, Umana, Fermo, Ascoli, Escolano, Jesi, Osimo, Camerino, Nocera, and Bishop Benedetto of Foligno.

On 10 March 1146, the assembled clergy participated in the consecration of the cathedral of Foligno, dedicated to S. John the Baptist, S. Feliciano, and S.

[5] Foligno Cathedral, of very early date, and possessing a beautiful crypt, was rebuilt beginning in 1133; in 1201 a wing, with a façade, was added, famous for its sculptures by Binello and Rodolfo (statues of Frederick Barbarossa and of Bishop Anselm), restored in 1903.

[13] Among the notable bishops of Foligno was Isidoro Chiari (1547–1555), a Benedictine biblical scholar and theologian, who participated in the early sessions of Council of Trent (1545–1547).

He did not attend the later sessions that resumed in 1551, but he submitted a memorandum urging the necessity of bishops being resident in their dioceses.

At the beginning of his tenure, Bishop Isidoro Chiari summoned and presided over a diocesan synod, which met on 14 November 1547.