Today, Bitterfeld is a long-distance station, which is served at two-hour intervals by ICEs from Berlin to Munich.

The station was electrified and electric trains ran to Dessau for the first time on 18 January 1911.

Further signal boxes, designated as "Rtl", "Rtll" and "Zd", were built for shunting operations in 1917.

Toward the end of the Second World War, freight operations came to a standstill from March 1945, since the bridge over the Mulde had been blown up.

The first electric trains to run through the station after the war ran to Roßlau on 15 March 1958.

Up to 1999, extensive reconstruction work took place on the entrance building and in the station forecourt.

With the changes following the end of Communism, the freight traffic in Bitterfeld decreased significantly, so that many goods tracks and signal boxes were closed by 2000.

The entrance building, which is to the east of the tracks, and the station forecourt are owned by Deutsche Bahn (2016).

At hourly intervals services on state bus route 434 run to Stumsdorf via Zörbig.