Michael Jai White, Byron Keith Minns, Tommy Davidson and Kym Whitley reprise their film roles as Black Dynamite, Bullhorn, Cream Corn and Honeybee, respectively.

The show continues the story of Black Dynamite, Bullhorn, Cream Corn, and Honey Bee as they engage in dangerous and over-the-top misadventures sometimes involving celebrities such as Michael Jackson, O. J. Simpson, Bill Cosby, Sidney Poitier, Richard Pryor, Don Cornelius, Dick Clark, Spike Lee, Mr. T, Orphan Arnold, James Brown, Isaac Hayes, Bob Marley, Bo Derek, Rick James, Elvis Presley, Fred Rogers, John Wayne Gacy, J. Edgar Hoover, and many others, as well as Black Dynamite's recurring nemesis, President Richard Nixon, who was also the main villain from the film.

The pilot episode features only an eleven-minute run time and was released on Adult Swim Video on August 8, 2011, and made its television debut over a year later on September 2, 2012.

However, once Michael gets on Black Dynamite's nerves, Cream Corn leaves, only to be subjected to the physical abuse of Jackson, who they all discover is actually an alien trying to take over the world.

Upon discovering he owes the IRS $60,000 in taxes, Black Dynamite decides to take on a job and he will soon regret: escorting a drug-addled and emotionally unstable Richard Pryor (voiced by Eddie Griffin) to the Sunset Strip for the biggest comedy performance of his career.

He joins O. J. on a lunar mission, but when O. J. bails at the last minute, Black Dynamite is trapped in space just as the rocket explodes in a major malfunction, making everyone believe that he is dead.

With the help of the spirit of Sun Tzu (voiced by Christopher "Kid" Reid), Black Dynamite must fight the flu and a horde of Isaac Washington robots to save his friends and pimps from all over the world.

The unseen shooter frames Black Dynamite and the Crew, and now they're on a run for their lives, trying to clear their name, pursued by every gay gang south of West Hollywood!

Back at the Whorephanage, all the sex-starved johns turn into horny zombies trying to hump their way into the building, but Honey Bee couldn't care less, she's not coming home!

On the Orphans' collective birthday, Black Dynamite brings them all to a show taping with their favorite TV white man, Mister Rogers (voiced by Corey Burton).

Now, you'd think that Fred Rogers was never a trained Special Forces killer and that he would definitely not kidnap all the Orphans in a deranged attempt to protect them from evil TV executives and that's exactly what doesn't not happen!

Cream Corn becomes a Soul Train dancer and Don Cornelius' old muscle Black Dynamite sees that just when he thought he was out…they pull him back in.

Between getting Scarecorn some game, Lionhorn a muzzle and the Tin Bee a set of balls, BD has to fight off the Wicked Bitch of the West Side and reach the Great and Powerful Mother#*?