They also began holding shows at clubs in the area, and after a short while they gained a large following of people of all ages in the town.

In 2003, on Black Stone Cherry Records, the band released their first demo on CD called Rock N' Roll Tape.

[6] The band supported Alter Bridge alongside Theory of a Deadman on a tour of Europe from October to November 2011.

The single along with a selection of Black Stone Cherry's hits, exclusive acoustic tracks, and exclusive live tracks from Download Festival 2013 featured on a special CD: "Black Stone Cherry - Hits, Rarities & Live" which came as bonus content with the June 2014 edition of Classic Rock Magazine.

[12] The band took a break from touring due to private circumstances, except a one-off home show in December 2014 in Kentucky.

In June, the band were the headliners of Download Festival's second stage, followed some supporting dates at smaller venues in the UK and Ireland.

In June, the band announced a UK arena tour as part of the Carnival of Madness package alongside Shinedown, Halestorm and Highly Suspect.

[14] On October 7, 2015, it was revealed that the band had signed to Mascot Label Group and had begun recording the follow-up to Magic Mountain for a 2016 release.

[20] On July 21, 2016, a video for the new single called "The Rambler" was released on YouTube which featured an appearance from Billy Ray Cyrus.

On August 5, 2020, the band announced their seventh album titled The Human Condition,[25] and released the lead single "Again" the following day.

[26] On June 2, 2021, Black Stone Cherry announced that bassist Jon Lawhon will take an indefinite hiatus from music and touring.

[27] In June, the band released their cover of Tracy Chapman's classic "Give Me One Reason" as the lead single from the deluxe edition of The Human Condition.