Blakesburg is a city in Wapello County, Iowa, United States.

[4] According to the United States Census Bureau, the city has a total area of 0.27 square miles (0.70 km2), all land.

There were 150 housing units at an average density of 554.4 per square mile (214.0/km2).

Hispanic or Latino persons of any race comprised 2.2% of the population.

There were 169 housing units at an average density of 625.9 per square mile (241.7/km2).

33.8% of all households were made up of individuals, and 15.2% had someone living alone who was 65 years of age or older.

There were 177 housing units at an average density of 666.8 per square mile (257.5/km2).

29.5% of all households were made up of individuals, and 16.9% had someone living alone who was 65 years of age or older.

Located three miles northeast of Blakesburg, the Airpower Museum features approximately 25 mostly pre-World War II aircraft on display as well as the Library of Flight, and early flight simulators, propellers, engines, and original art.

Students grades 7–12 attend the Eddyville–Blakesburg Junior/Senior High School in neighboring Eddyville.