He subsequently spent most of his career in Italy, making 280 Serie A appearances for Torino, Parma, Napoli, Genoa and Bologna.

Džemaili imposed a strong influence on the field as he possessed accurate passing capabilities as well as a fast and aggressive approach to the game.

[7] Former Bolton manager Sam Allardyce was quoted as saying, "Blerim is a fantastic player, who has played for the best team in Switzerland for the past three years.

[9] He made his debut as a substitute in the club's FA Cup defeat to Sheffield United in what proved to be his only showing of the 2007–08 campaign.

[14][15] After having played just once for Torino at Coppa Italia,[16] Džemaili completed a loan move to Parma on 31 August 2009, with an option to sign the 50% registration rights of the player at the end of season.

[19] On 25 June 2011, Džemaili was signed by Napoli for €9 million[19] with Fabiano Santacroce (loan) and Manuele Blasi (free)[19] going the other way to Parma.

[22] Džemaili has also appeared six times in the UEFA Champions League group stages and helped Napoli into the final 16.

[20] Džemaili had appeared regularly for the side in the Coppa Italia, and played the entire match in the final in which they defeated Juventus 2–0.

[25] On 1 September 2014, Džemaili signed a three-year contract with Turkish Süper Lig team Galatasaray for a €2.35 million transfer fee.

On 9 December 2016, Montreal Impact president and Bologna chairman Joey Saputo announced that Džemaili would join the Major League Soccer (MLS) team on loan in the spring of 2017 as a Designated Player.

[37] On 6 September 2013, Džemaili scored his first international goal from a penalty kick in a 4–4 home draw in a World Cup qualifier against Iceland.

[38] On 2 June 2014, Džemaili was named in Switzerland's 2014 World Cup squad by national coach Ottmar Hitzfeld.

[41][42] Džemaili scored his third international goal against San Marino on 10 October 2014 in UEFA Euro 2016 qualifying, heading-in Ricardo Rodríguez's corner to give the Swiss a 3–0 lead in an eventual 4–0 victory.

Džemaili scored twice for Switzerland on 10 June 2015, the second of which came from a direct free-kick in a 3–0 friendly victory over Liechtenstein at Stockhorn Arena in Thun.

[44] During his time in Serie A, Džemaili differed from most other players in the attacking midfield position due to his box-to-box approach to the role and hard-running style.

[45][46][47][48][49][50][51][52][53][54][55][56] In 2015, Džemaili married Shkoder-born Albanian model Erjona Sulejmani[57] who, in the same year, gave birth to their eldest son, Luan.