Its most popular products included Polident denture cleanser, Poli-Grip denture adhesive, Dentu-Creme denture toothpaste, Nytol sleeping pill, Tegrin medicated shampoo for psoriasis, Lava hand soaps (acquired from Procter & Gamble), Beano and Phazyme anti-gas products, Balmex diaper rash ointments, and Sensodyne desensitizing toothpaste.

[2][3] The company was founded in 1907 by Alexander Block, a Russian immigrant who had a small drugstore on Fulton Street in Brooklyn, New York.

[4] Although Alexander Block built the company largely through acquisitions, he developed the Polident brand internally during the 1930s.

[5] In 1948, Block Drug rolled out the Ammi-i-Dent tooth powder, and in the early 1950s, the company developed Nytol.

In addition, the company never held annual meetings or issued proxy statements.