The Blood Mountain Wilderness was designated in 1991 and currently consists of 7,800 acres (32 km2).

In November, 1999, three fires burned through parts of the Blood Mountain Wilderness and the Chattahoochee National Forest.

The Wilderness includes 10.75 miles (17.30 km) of the Appalachian Trail, which may be the most heavily used portion of the AT.

Due to conflicts with black bears, in 2012 the Forest Service implemented a seasonal requirement for all overnight campers to carry bear-resistant canisters.

The requirement goes into effect every year, from March 1 to June 1, and it encompasses all areas within quarter mile of the AT, from Jarrard Gap to Neels Gap.