[1] Bloodstrike features a squad of assassins, each of whom is a super-powered operative who died in the line of duty and was resurrected by a secret government program called Project Born Again.

The team members all require ongoing treatment sessions to stay alive and are thus unable to ever leave the project or opt against participating in a mission.

Other members include the four-armed combat expert Fourplay, the savage ex-villain Deadlock, the power-armored Shogun and the enigmatic Tag, who could force people to "freeze in place" by touching them.

[8] At one point the government added the recently diagnosed HIV-positive character of Chapel to the roster,[9] making him the only living member of the team.

On August 20, 2012, Liefeld was set to produce a Bloodstrike film adaptation with Adi Shankar's 1984 Private Defense Contractors and Brooklyn Weaver's Energy Entertainment.

Over the years, interest had been expressed in the property by individuals such as Akiva Goldsman and Graham King, and production companies such as Netflix, which optioned the development rights, but these eventually expired without any produced results.

[15] Liefeld explained in the caption that accompanied the trailer that he released it in the hopes of spurring renewed interest in producing a Bloodstrike film, saying, "When taking a comic book from page to screen there are always hurdles, screenplay, screenwriters, talent that attach and move on.