The road was previously occupied by Wong Nai Chung Village (黃泥涌村), which was settled by the Ngs (吳) and Yips (葉), both Hakkas from the Mainland,[1] before British Colonization on Hong Kong Island.

[2] Wong Nai Chung Village was replaced with residential buildings in the 1920s, as a consequence of urban development.

[1] The street is named after the former "Blue Pool", a natural feature[3] near the former Wong Nai Chung Village, in which people could bathe until around World War I.

[4][5] On 22 December 1941, a massacre of Chinese civilians by Japanese troops occurred at Blue Pool Road.

The lower end of Blue Pool Road is located near the Hong Kong Tramways Happy Valley terminus.