It stars Harvey Keitel leading an ensemble cast, including Giancarlo Esposito, Roseanne Barr, Michael J.

Fox, Lily Tomlin, Victor Argo, Mira Sorvino, Lou Reed, Keith David, Jim Jarmusch, Jared Harris, RuPaul, and Madonna.

During production of Smoke, Keitel and the others ad-libbed scenes in-character between takes and a sequel was made using this improvised material.

Her bilingual duet with David Byrne, "God's Child (Baila Conmigo)", appears on the film's soundtrack.

The store owner's frustrated wife Dot (Roseanne Barr) is one of them, and one of the plotlines follows her attempts to seduce Auggie.