In his major league debut, he collected his first hit, a single off Atlanta Braves pitcher Jay Ritchie, and was promptly caught stealing.

Heise was part of a proposed trade package along with Ed Kranepool and Amos Otis when the Mets attempted to acquire the Braves' Joe Torre who went to the St. Louis Cardinals for Orlando Cepeda instead.

Heise was sent along with Jim Gosger from the Mets to the San Francisco Giants for Ray Sadecki and Dave Marshall on December 12, 1969.

He spent most of the season backing up Hal Lanier at short until an injury to Ron Hunt made him the starting second baseman for the month of September.

[5] Heise had played in thirteen games, going hitless in 11 at bats when he was traded to the Milwaukee Brewers for Floyd Wicker on June 1, 1971.

Heise’s playing time was significantly cut in 1973, due to many new acquisitions by the Brewers, including Don Money, Tim Johnson, and Pedro García..

[7] Heise spent the majority of his time with the Cardinals organization with the AAA Tulsa Oilers, with his only trial being in all three games of a series against the Houston Astros in July.