During Sippio's professional career, he played for thirteen different teams in four different leagues, including the NFL's Miami Dolphins, Kansas City Chiefs, and Detroit Lions.

Sippio played in 16 games in his second season with Dallas, recording 61 receptions for 863 yards and 22 touchdowns and added 30.5 tackles, two interceptions and nine passes broken up.

On May 13, 2009, due to the injury of leading wide receiver Donovan Morgan, the Chicago Slaughter of the Continental Indoor Football League signed Sippio.

[3] The Arena Football League halted operations for the 2009 season, preventing Sippio from re-signing with the Rush or any other AFL team.

[6] Sippio scored 6 TDs (4 receiving, 2 rushing), including a game-winner with just 8.7 seconds remaining, in Orlando's 73–69 victory over #1 seed Jacksonville in the first round of the 2010 Arena Football Playoffs.

[7] On May 25, 2012, Bobby Sippio was arrested and charged with attempted murder, armed robbery, aggravated battery, and kidnapping over an incident involving his girlfriend's brother.

The man, Sergio Moore, suffered a broken nose, swollen left hand and wrist, and cuts to the head and cheek.