He began his political career in 1883 when he entered the Croatian Parliament as a member elected in the Serb district.

Advocating for harmony and a political alliance with the Croats in the Austro-Hungarian monarchy, as the leader of the Serb Independent Party, Bogdan Medaković actively participated in the adoption of the Zadar Resolution with Svetozar Pribićević, which resulted in the creation of the Croat-Serb Coalition.

As the then President of the Parliament in 1918, he declared the severance of state-legal ties with the Hungarian and Austrian empires, which opened the way to the creation of the Kingdom of Serbs Croats and Slovenes.

Medaković was a determined fighter in the fight for the preservation of church-school autonomy, for freedom of speech and for the parliamentary system in then Croatia.

In Zagreb, he built one of the most beautiful residential palaces on Zrinjski Square 15, which was originally almost the same as the Adam House in Budapest (Bródy Sándor Street No.