Bolshoye Polpino (Russian: Большо́е По́лпино) is an urban locality (urban-type settlement) under the administrative jurisdiction of the town of oblast significance of Bryansk of Bryansk Oblast, Russia.

Population: 5,859 (2021 Census);[4] 6,356 (2010 Census);[1] 4,613 (2002 Census);[5] 6,374 (1989 Soviet census).

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