In 1899, the United States Department of War conducted a census of Puerto Rico finding that the population of Boquerón was 1,185.

The Cabo Rojo National Wildlife Refuge is a habitat for a number of native bird species, including the endangered yellow-shouldered blackbird, also known as mariquita de Puerto Rico or capitán.

[17] According to local folklore, after the Puerto Rican pirate Roberto Cofresí shared some of his treasure with his family and friends, he would hide what was left over in a cave located in "Barrio Pedernales" which is just north of Boquerón Bay.

It is home to many restaurants offering local, international, and fusion cuisine which feature the excellent seafood that Cabo Rojo is renowned for.

[19] El Poblado is also populated by bars for every preference, from pool halls to holes-in-the-wall, many providing a variety of flavored mojitos and other mixed drinks.