It is located in the westernmost Province of Chiriquí, about 60 kilometres (37 mi) from the border with Costa Rica, and lies on the Caldera River, in Panama's green mountain highlands.

Its scenic location, temperature, and natural environment make it popular with Panamanians and attracts tourists and retirees from all over the world.

In the Caldera region you can find petroglyphs (a rock carving, especially a prehistoric one) that are evidence of the ancient settlements in the area.

During the Spanish colonization, the highlands area was an isolated refuge for the indigenous tribes like the Ngöbe and the Misquito due to the topographic terrain.

The colonization of Boquete only began in earnest in the second half of the nineteenth century, by locals from Bugaba, Gualaca, and David, and foreigners from Yugoslavia, France, Germany, and other European countries.

It became the first performance venue in the community in November 2009, when BCP held its grand opening of a refurbished restaurant and bar in the center of Boquete alongside the Caldera River.

Visitors to Boquete are frequently advised to visit BCP on Tuesday mornings because it is such an integral part of the community.

Boquete also hosts an annual Coffee and Flower Fair, with attractions for those older and younger, and beautiful displays of colorful natural arrangements and scents.

Ex-pats are attracted by the comfortable climate, excellent potable water, and clean air, as well as by the tranquility and Panama's relatively low cost of living.

[7] Kris Kremers and Lisanne Froon were Dutch students who disappeared on 1 April 2014, while hiking in the vicinity of Boquete.

Their cause of death could not be determined definitively, but Dutch authorities working with forensic and search-rescue investigators thought it likely the students had accidentally fallen from a cliff after becoming lost.