The Bosanski Šamac ethnic cleansing refers to war crimes, including murder, looting, ethnic cleansing and persecution committed against Bosniaks and Croats in the Bosanski Šamac area by the Yugoslav People's Army and Serb paramilitary units from 17 April until November 1992 during the Bosnian war.

[2] The UN-backed International Criminal Tribunal for the former Yugoslavia (ICTY) classified it as a crime against humanity and sentenced nine Serb officials, including Jovica Stanišić and Franko Simatović, who served in the State Security Service (SDB) within the Ministry of Internal Affairs of Serbia, making it the only case in the history of the tribunal for which officials from Serbia were sentenced for crimes in Bosnia and Herzegovina.

Bosanski Šamac was a strategically important municipality for the Bosnian Serb forces, who wanted to include it into its "Posavina Corridor" that would link Serb-coveted territories in Croatia and Bosnia and Herzegovina with Serbia.

[4] Prior to the start of the Bosnian War, incidents of shootings, grenade explosions, sabotage and violence escalated in Bosanski Šamac.

[17] At least 16 civilians were killed when 50 prisoners were rounded up in an internment camp by the Grey Wolves paramilitary group led by Slobodan Miljković.

[18] The UN-backed International Criminal Tribunal for the former Yugoslavia (ICTY) sentenced nine Serb officials for war crimes in Bosanski Šamac.

[23] Stojan Župljanin and Mićo Stanišić were sentenced to 22 years in prison, including for crimes of persecution, torture, unlawful detention, forcible transfer and deportation, and wanton destruction of towns and villages.