In the 16th century the medical doctor Juraj Purkircher (1530-1578), a citizen of Bratislava (known under various names throughout its history), had a small botanical garden next to his house which was visited by the famous botanist Carolus Clusius during his trip to the Kingdom of Hungary.

Its construction was supervised by professor František Nábělek, Head of the Botanical Office of the Slovak University, who became its first director.

As the most suitable location for its establishment, it was decided to lay the foundations of the new botanical garden at the place around the villa of Mr. Lafranconi in Mlynská dolina.

The land lot in question had 6,6 hectares of space, a constant water source due to the presence of the river Vydrica and the location was convenient for both students and citizens of Bratislava.

[6] The area of the botanical garden is also occasionally used for events, exhibitions and open-air summer musical concerts and it is a desired place for weddings.