It is located at Am Kirchtor 3 in the city of Halle, Saxony-Anhalt, Germany, and open daily in the warmer months.
The garden's origins can be traced back to 1698 when Frederick III, Prince Elector of Brandenburg donated parts of his hortus medicus to the university in Halle.
In 1787 it was enlarged to its present size by Karl Christoph von Hoffmann (1735-1801), university chancellor, in response to activities of garden directors Johann Reinhold Forster (1729-1798), who participated in Captain James Cook's second world expedition, and Philipp Kaspar Junghans (1736-1798).
During the 20th century, additional modern green houses were built and old ones renovated, including the 1994 reconstruction of the Victoria greenhouse.
It also contains an important collection of Central Asian plants, especially from Mongolia, which is believed to be one of the largest such collections outside Russia and Mongolia, and preserves some rare and extinct plants with emphasis on the local region of Saxony-Anhalt, including Artemisia rupestris, as well as exotics such as Carlina diae (Asteraceae) from Crete and Sophora toromiro from the Easter Islands.