In 1663 a Hortus Medicus was created by direction of Eberhard III, Duke of Württemberg (1614–74), with university gardener appointed in 1666.
The first greenhouse was completed in 1744, and noted botanist Johann Georg Gmelin (1709-1755) appointed director in 1751.
In 1804 a new garden was established by decree of King Frederick of Württemberg (1754-1816) under the leadership of Professor Carl Friedrich Kielmeyer (1765-1844), which grew and flourished throughout the first half of the nineteenth century.
By 1809 it contained four greenhouses and a lecture hall, with its first seed catalog published in 1820, and from 1818-1825 its plants were reorganized according to the system of Antoine Laurent de Jussieu.
[citation needed] The fuchsias are gathered in a glass and steel pavilion, built in 2001 for the 500th anniversary of the birth of Leonhart Fuchs.