Bothwell was a federal electoral district in the Canadian province of Ontario, which was represented in the House of Commons of Canada from 1867 to 1904.

At its creation in 1867, Bothwell consisted of the Kent County townships of Bothwell, Camden, Dresden, Howard, Orford, Ridgetown, Thamesville and Zone, and the Lambton County townships of Dawn, Euphemia and Sombra.

In 1882, the Townships of Euphemia, Orford and Howard were excluded from the riding, and the township of Chatham, the villages of Wallaceburg, Dresden and Thamesville, and the town of Bothwell were added to the riding.

This riding elected the following members of the House of Commons of Canada:

Mr. David Mills was appointed Minister of the Interior and Superintendent General of Indian Affairs, 24 October 1876: