The women's flyweight (51 kilograms) event at the 2010 Asian Games took place from 21 to 25 November 2010 at Lingnan Mingzhu Gymnasium, Foshan, China.

[1] Like all Asian Games boxing events, the competition was a straight single-elimination tournament.

A total of 13 women from 13 countries competed, limited to fighters whose body weight was less than 51 kilograms.

She beat Annie Albania of the Philippines 7–5 in the final bout in Foshan Gymnasium.

Ren Cancan became the first ever women's boxing champion at the Asian Games.