The women's middleweight boxing event at the 2020 Summer Olympics took place between 28 July and 8 August 2021 at the Ryōgoku Kokugikan.

Reigning World Champion Lauren Price of Great Britain won the event.

Light heavyweight World Champion Zemfira Magomedalieva of Russia also qualified at this weight (the middleweight is the heaviest Olympic women's class), and won a bronze medal.

[4] The 2012 and 2016 Olympic champion, Claressa Shields of the United States, turned professional and did not attempt to qualify.

Judges consider "number of blows landed on the target areas, domination of the bout, technique and tactical superiority and competitiveness."