After graduating from junior, Lukowich was traded from the Islanders to the Dallas Stars for a third round pick in the 1997 NHL Entry Draft on June 1, 1996.

In 1999–2000, he remained with the Stars full-time and recorded four points over 60 games in his NHL rookie season, averaging nearly 12 minutes of ice time.

[2] Following a five-goal, 19-point season in 2003–04, Lukowich earned his second Stanley Cup championship, helping the Lightning to their first title with a seven-game victory over the Calgary Flames in the finals.

Due to the 2004–05 NHL lockout, Lukowich signed as a free agent with the Fort Worth Brahmas of the Central Hockey League (CHL) on September 21, 2004.

With the NHL set to resume with the 2005–06 season, he became an unrestricted free agent and signed with the team that originally drafted him, the New York Islanders, on August 11, 2005.

[3] Lukowich scored eight points in his only season with the Sharks before being traded once more, along with defenceman Christian Ehrhoff on August 28, 2009, to the Vancouver Canucks in exchange for prospects Daniel Rahimi and Patrick White.

[7] In June 2013, Lukowich signed a contract with the Western Hockey League's Lethbridge Hurricanes to become the team's assistant coach.