Bradford was established in the early 19th century, the steep drop of the Waits River recognized as a source of water power for industrial use.

Asa Low spearheaded development of that industry, building a brick grist mill in 1847.

The historic district designated in 1975 comprises 81 commercial, public, and religious buildings showcasing architectural styles from Federal and Greek Revival to Italianate and Romanesque.

[5] Some of Bradford's more significant historic buildings include:[5] According to the United States Census Bureau, the village had a total area of 0.5 square mile (1.3 km2), all land.

31.1% of all households were made up of individuals, and 14.6% had someone living alone who was 65 years of age or older.