Each cover featured an unnamed mascot which vaguely resembled the 1980s children's TV puppet Gilbert the Alien.

Its sibling titles included the direct Viz clone Gas and reprint anthology Talking Turkey.

Brain Damage was published until volume 3, number 4 (issue 28), and was then replaced with Elephant Parts which abandoned the political aspects in favour of surreal nonsense.

Elephant Parts supposedly incorporated "The Damage", but as it was printed on different paper stock and with a markedly changed editorial, was effectively a different magazine.

On 18 June 2009, all rights to the Brain Damage comic series were acquired by Untitled Project Productions in Brooklyn, NY.