"[4] Neighbors premiered Off-Broadway at the Public Theater/Public LAB in February - March 2010,[5][6] and was presented at the Matrix Theatre Company, Los Angeles in August 2010, directed by Nataki Garrett.

The play was produced by the Mixed Blood Theater, Minneapolis, Minnesota in September to October 2011, also directed by Nataki Garrett.

[9] It ran Off-Off-Broadway at the Soho Rep in April 2014 to June 2014 and then at the Polonsky Shakespeare Center, Brooklyn, New York, from February 2015 to March 29, 2015.

[13][14] Michael Billington in his review of the 2019 production at the Donmar Warehouse (London), wrote: "...he appropriates the classic American family drama with results that are both gravely serious and mordantly funny...What is exhilarating about the play is that Jacobs-Jenkins pushes everything to the limits.

Directed by Lileana Blain-Cruz, the cast featured Tonya Pinkins, Philippe Bowgen, Rachael Holmes, Greg Keller and Trezana Beverley.

[18] War opened at the Lincoln Center LCT3 series Off-Broadway on May 21, 2016 in previews, officially on June 6, directed by Lileana Blain-Cruz, and ran through July 3.

[23] Directed by Lila Neugebauer, the cast includes Jocelyn Bioh, Brooke Bloom, Michael Braun, Marylouise Burke, Louis Cancelmi, Lilyana Tiare Cornell, David Patrick Kelly, Lakisha Michelle May and Chris Perfetti.

[24][23][25] Jacobs-Jenkins explained the play: "The concept...is that every night there’ll be a different Everyman, chosen by lottery, so the cast will shift a lot.

The play is a contemporary version of Euripides’ Greek tragedy The Bacchae, and contains dance music and live-streaming video.

He is joined by Annie Baker, with whom he served as co-artistic directors for the MFA playwriting program at Hunter College of the City University of New York.

[32] His play Purpose will transfer to Broadway's Helen Hayes Theater beginning in February of 2025 after a critically acclaimed run at Chicago's Steppenwolf Theatre.

[38] The Pulitzer committee wrote: "A play of wit and irony that deftly transports the audience from satire to thriller and back again.

[42] A production was staged at San Francisco's American Conservatory Theater opening in February 2020 and closed early due to the COVID-19 pandemic.

[53] The foundation noted, in part: "Many of Jacobs-Jenkins’s plays use a historical lens to satirize and comment on modern culture, particularly the ways in which race and class are negotiated in both private and public settings.